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Invitrogen
ITPA Polyclonal Antibody
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Product Details
PA5-54614
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human ITPA. Recombinant protein control fragment (Product #RP-91737).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: GFEDKSAYAL CTFALSTGDP SQPVRLFRGR TSGRIVAPRG CQDFGWDPCF QPDGYEQTYA EMPKAEKNAV SHRFRALLEL QEYFGSLAA
Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 83%.
Target Information
Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: inosine triphosphatase (nucleoside triphosphate pyrophosphatase); Inosine triphosphate pyrophosphatase; inosine triphosphate pyrophosphohydrolase; ITPase; My049 protein; Non-canonical purine NTP pyrophosphatase; Non-standard purine NTP pyrophosphatase; NTPase; Nucleoside-triphosphate diphosphatase; Nucleoside-triphosphate pyrophosphatase; Putative oncogene protein hlc14-06-p
Gene Aliases: C20orf37; dJ794I6.3; HLC14-06-P; ITPA; ITPase; My049; NTPase; OK/SW-cl.9
UniProt ID: (Human) Q9BY32
Entrez Gene ID: (Human) 3704
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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