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Invitrogen
NMT1 Polyclonal Antibody
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FIGURE: 1 / 1
NMT1 Antibody (PA5-54643) in WB
Western blot analysis of NMT1 in control (vector only transfected HEK293T lysate) and NMT1 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells). Samples were probed using a NMT1 Polyclonal Antibody (Product # PA5-54643).
Product Details
PA5-54643
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human NMT1. Recombinant protein control fragment (Product #RP-93326).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: MADESETAVK PPAPPLPQMM EGNGNGHEHC SDCENEEDNS YNRGGLSPAN DTGAK
Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 91%.
Target Information
NMT1 is involved with Myristate, a rare 14-carbon saturated fatty acid, is cotranslationally attached by an amide linkage to the N-terminal glycine residue of cellular and viral proteins with diverse functions. N-myristoyltransferase (NMT EC 2.3.1.97) catalyzes the transfer of myristate from CoA to proteins. N-myristoylation appears to be irreversible and is required for full expression of the biologic activities of several N-myristoylated proteins, including the alpha subunit of the signal-transducing guanine nucleotide-binding protein (G protein) GO (GNAO1 MIM 139311).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alternative, short form NMT-S; Glycylpeptide N-tetradecanoyltransferase 1; HsNMT1; long form, NMT-L; Myristoyl-CoA:protein N-myristoyltransferase 1; Peptide N-myristoyltransferase 1; Protein-lysine myristoyltransferase NMT1; type I N-myristoyltransferase; unnamed protein product
Gene Aliases: HsNMT1; NMT; NMT1
UniProt ID: (Human) P30419
Entrez Gene ID: (Human) 4836
in utero embryonic development
N-terminal peptidyl-glycine N-myristoylation
regulation of rhodopsin mediated signaling pathway
cellular response to nutrient levels
cellular ketone metabolic process
protein localization to membrane
positive regulation of protein localization to lysosome
positive regulation of establishment of protein localization to mitochondrion
positive regulation of TORC1 signaling
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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