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Invitrogen
HRSP12 Polyclonal Antibody
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Product Details
PA5-54808
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human HRSP12. Recombinant protein control fragment (Product #RP-93791).
Conjugate
Form
Liquid
Concentration
0.10 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: GCDFTNVVKT TVLLADINDF NTVNEIYKQY FKSNFPARAA YQVAALPKGS RIEIEAVAIQ GP
Highest antigen sequence identity to the following orthologs: Mouse - 81%, Rat - 89%.
Target Information
Endoribonuclease responsible for the inhibition of the translation by cleaving mRNA. Inhibits cell-free protein synthesis. Cleaves phosphodiester bonds only in single-stranded RNA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 14.5 kDa translational inhibitor protein; 2-iminobutanoate/2-iminopropanoate deaminase; Heat-responsive protein 12; hp14.5; L-PSP; Liver perchloric acid-soluble protein; perchloric acid soluble protein; perchloric acid-soluble protein; perchrolic acid soluble protein; Reactive intermediate imine deaminase A homolog; ribonuclease UK114; rp14.5; Translation inhibitor L-PSP ribonuclease; translational inhibitor p14.5; translational inhibitor protein p14.5; UK114; UK114 antigen homolog
Gene Aliases: hp14.5; HR12; HRP12; HRSP12; P14.5; PSP; PSP1; RIDA; UK114
UniProt ID: (Mouse) P52760, (Rat) P52759, (Human) P52758
Entrez Gene ID: (Mouse) 15473, (Rat) 65151, (Human) 10247
nuclease activity
endonuclease activity
hydrolase activity
endoribonuclease activity, producing 3'-phosphomonoesters
deaminase activity
long-chain fatty acid binding
phosphoric ester hydrolase activity
protein homodimerization activity
ion binding
T/G mismatch-specific endonuclease activity
poly(A) RNA binding
retroviral 3' processing activity
transition metal ion binding
platinum binding
xenon atom binding
RNA binding
mRNA binding
protein binding
2-iminobutanoate/2-iminopropanoate deaminase
2-iminobutanoate deaminase activity
2-iminopropanoate deaminase activity
deaminase
negative regulation of translation
negative regulation of epithelial cell proliferation
RNA phosphodiester bond hydrolysis, endonucleolytic
kidney development
brain development
lung development
response to lipid
G1 to G0 transition
response to salt
mRNA catabolic process
lipid metabolic process
posttranscriptional regulation of gene expression
negative regulation of gene expression
L-threonine catabolic process to glycine
mRNA destabilization
regulation of primary metabolic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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