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Invitrogen
CtBP2 Polyclonal Antibody
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Product Details
PA5-54822
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human CtBP2. Recombinant protein control fragment (Product #RP-93157).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: VVDPSSAAAP EGSTGVAPGA LNRGYGPARE SIPSKMAYET YEADLSTFQG PGGKRTVLPE FLAFLRAEGL AEATLGALLQ QGFDSPAVLA TLEDADIKSV APNL
Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 88%.
Target Information
This gene produces alternative transcripts encoding two distinct proteins. One protein is a transcriptional repressor, while the other isoform is a major component of specialized synapses known as synaptic ribbons. Both proteins contain a NAD+ binding domain similar to NAD+-dependent 2-hydroxyacid dehydrogenases. A portion of the 3' untranslated region was used to map this gene to chromosome 21q21. 3; however, it was noted that similar loci elsewhere in the genome are likely. Blast analysis shows that this gene is present on chromosome 10.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: C-terminal-binding protein 2; CTBP2; phosphoprotein; CtBP; transcriptional corepressor; ribeye; RP11-59C5.2; unnamed protein product
Gene Aliases: CTBP2
UniProt ID: (Human) P56545
Entrez Gene ID: (Human) 1488
transcription cofactor binding
transcription corepressor binding
transcription coactivator activity
transcription corepressor activity
protein binding
oxidoreductase activity
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
protein kinase binding
identical protein binding
macromolecular complex binding
NAD binding
DNA-binding transcription factor binding
negative regulation of transcription from RNA polymerase II promoter
regulation of transcription from RNA polymerase II promoter
negative regulation of cell proliferation
viral genome replication
cell differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of retinoic acid receptor signaling pathway
white fat cell differentiation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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