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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: GQLQPSRPTR ARGTCSVEDP LLVCQKEPGK PRMVKSVGSV GDSPREPRRT VSESVIAVKA SFPSSALPPR TGVALGRKLG SHSVASCAPQ LLGDRRVGAG H
Highest antigen sequence identity to the following orthologs: Mouse - 61%, Rat - 66%.
Required for the export of polyadenylated mRNAs from the nucleus (PubMed:19364924). Enhances ACVR1B-induced SMAD-dependent transcription. Binds to single-stranded DNA but not to double-stranded DNA in vitro. Involved in RNA cleavage. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Smad-interacting CPSF-like factor; Zinc finger CCCH domain-containing protein 3
Gene Aliases: KIAA0150; SMICL; ZC3H3; ZC3HDC3
Entrez Gene ID: (Human) 23144
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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