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Invitrogen
NCDN Polyclonal Antibody
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Product Details
PA5-54863
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human NCDN. Recombinant protein control fragment (Product #RP-93982).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: PEYEGIWADL QELWFLGMQA FTGCVPLLPW LAPAALRSRW PQELLQLLGS VSPNSVKPEM VAAYQGVLVE LARANRLCRE AMRLQAGEET ASHYRMAA
Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.
Target Information
Probably involved in signal transduction, in the nervous system, via increasing cell surface localization of GRM5 and positively regulating its signaling. Required for the spatial learning process. Acts as a negative regulator of Ca(2+)-calmodulin-dependent protein kinase 2 (CaMK2) phosphorylation. May play a role in modulating melanin-concentrating hormone-mediated functions via its interaction with MCHR1 that interferes with G protein-coupled signal transduction. May be involved in bone metabolism. May also be involved in neurite outgrowth.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: M-Sema F-associating protein of 75 kDa; minisatellite 10ae detected by probe MMS10; Neurite outgrowth-related protein from the rat brain; Neurochondrin; neurochondrin-1; neurochondrin-2; Norbin
Gene Aliases: AU042419; KIAA0607; mKIAA0607; MMS10-AE; Ms10ae; NCDN; Norbin; Sfap75
UniProt ID: (Human) Q9UBB6, (Mouse) Q80TW1, (Rat) O35095
Entrez Gene ID: (Human) 23154, (Mouse) 26562, (Rat) 89791
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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