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Invitrogen
PPP1R12B Polyclonal Antibody
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Product Details
PA5-55001
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human PPP1R12B. Recombinant protein control fragment (Product #RP-94025).
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: GTGINFWTKD EDETDGSEEV KETWHERLSR LESGGSNPTT SDSYGDRASA RARREAREAR LATLTSRVEE DSNRDYKKLY ESALTENQKL KTKLQEAQLE LADIKS
Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 92%.
Target Information
Myosin phosphatase is a protein complex comprised of three subunits: a catalytic subunit (PP1c-delta, protein phosphatase 1, catalytic subunit delta), a large regulatory subunit (MYPT, myosin phosphatase target) and small regulatory subunit (sm-M20). Two isoforms of MYPT have been isolated--MYPT1 and MYPT2, the first of which is widely expressed, and the second of which may be specific to heart, skeletal muscle, and brain. Each of the MYPT isoforms functions to bind PP1c-delta and increase phosphatase activity. This locus encodes both MYTP2 and M20. Alternatively spliced transcript variants encoding different isoforms have been identified. Related pseudogenes have been defined on the Y chromosome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Myosin phosphatase target subunit 2; Myosin phosphatase-targeting subunit 2; protein phosphatase 1 regulatory (inhibitor) subunit 12B isoform PPP1R12B_1; protein phosphatase 1 regulatory (inhibitor) subunit 12B isoform PPP1R12B_2; Protein phosphatase 1 regulatory subunit 12B; protein phosphatase 1, regulatory (inhibitor) subunit 12B
Gene Aliases: MYPT2; PP1bp55; PPP1R12B
UniProt ID: (Human) O60237
Entrez Gene ID: (Human) 4660
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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