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Invitrogen
Actin-like 7B Polyclonal Antibody
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FIGURE: 1 / 9
Actin-like 7B Antibody (PA5-55147) in IHC
Immunohistochemical staining of Actin-like 7B in human cerebral cortex, duodenum, kidney and testis using Actin-like 7B Polyclonal Antibody (Product # PA5-55147) (A) shows similar protein distribution across tissues to an independent Actin-like 7B Polyclonal Antibody (B).
Product Details
PA5-55147
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human Actin-like 7B. Recombinant protein control fragment (Product #RP-93002).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: LTNYLMQLLN EAGHAFTDDH LHIIEHIKKK CCYAAFLPEE ELGLVPEELR VDYELPDGKL ITIGQERFRC SEMLFQPSL
Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 86%.
Target Information
The protein encoded by this gene is a member of a family of actin-related proteins which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene, and related gene, ACTL7A, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7B gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. Unlike ACTL7A, the ACTL7B gene is expressed predominantly in the testis, however, its exact function is not known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: actin-like 7-beta; Actin-like protein 7B; Actin-like-7-beta; MGC151192; MGC151194; RP11-3J11.2; testis tissue sperm-binding protein Li 43a; unnamed protein product
Gene Aliases: ACTL7B; Tact1
UniProt ID: (Human) B2R9Q2
Entrez Gene ID: (Human) 10880
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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