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          • Primary Antibodies ›
          • HOOK3 Antibodies

          Invitrogen

          HOOK3 Polyclonal Antibody

          1 Published Figure
          1 Reference
          View all (8) HOOK3 antibodies

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          Cite HOOK3 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (2)
          • Published Figures (1)
          HOOK3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          HOOK3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 3

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          HOOK3 Antibody (PA5-55172) in IHC (P)

          Immunohistochemical analysis of HOOK3 in human cerebral cortex using HOOK3 Polyclonal Antibody (Product # PA5-55172) shows strong cytoplasmic positivity in neuronal cells. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
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          View Product

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          HOOK3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          HOOK3 Antibody in Western Blot (WB)
          HOOK3 Antibody in Immunocytochemistry (ICC/IF)
          HOOK3 Polyclonal Antibody

          Product Details

          PA5-55172

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          0.04-0.4 µg/mL
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:200
          -

          Immunocytochemistry (ICC/IF)

          -
          View 1 publication 1 publication
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human HOOK3. Recombinant protein control fragment (Product #RP-93890).
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.1 mg/mL

          Amount

          10 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2642515

          Product Specific Information

          Immunogen sequence: KEEIAQRCHE LDMQVAALQE EKSSLLAENQ VLMERLNQSD SIEDPNSPAG RRHLQLQTQL EQLQEETFRL EA

          Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 58%.

          Target Information

          Hook proteins are cytosolic coiled-coil proteins that contain conserved N-terminal domains, which attach to microtubules, and more divergent C-terminal domains, which mediate binding to organelles. The Drosophila Hook protein is a component of the endocytic compartment.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: h-hook3; hHK3; hook homolog 3; Protein Hook homolog 3; unnamed protein product

          View more View less

          Gene Aliases: HK3; HOOK3

          View more View less

          UniProt ID: (Human) Q86VS8

          View more View less

          Entrez Gene ID: (Human) 84376

          View more View less

          Function(s)
          protein binding microtubule binding dynactin binding identical protein binding dynein light chain binding dynein intermediate chain binding dynein light intermediate chain binding
          Process(es)
          endosome organization lysosome organization endosome to lysosome transport protein transport interkinetic nuclear migration cytoskeleton-dependent intracellular transport cytoplasmic microtubule organization microtubule anchoring at centrosome early endosome to late endosome transport negative regulation of neurogenesis Golgi localization protein localization to centrosome neuronal stem cell population maintenance protein localization to perinuclear region of cytoplasm
          It has to be done as per old AB suggested Products section.

          Disclaimer

          Close

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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