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Invitrogen
RNF213 Polyclonal Antibody
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Product Details
PA5-55418
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human RNF213. Recombinant protein control fragment (Product #RP-89516).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: KDPVCLPCDH VHCLRCLRAW FASEQMICPY CLTALPDEFS PAVSQAHREA IEKHARFRQM CNSFFVDLVS TICFKDNAPP EKEVIESLLS LLFVQKGRLR DAAQRHCEHT KSLSPFNDVV DKTPVIRSVI LKLLLKYS
Highest antigen sequence identity to the following orthologs: Mouse - 78%, Rat - 79%.
Target Information
RNF213 is an E3 ubiquitin-protein ligase involved in angiogenesis. Involved in the non-canonical Wnt signaling pathway in vascular development: acts by mediating ubiquitination and degradation of FLNA and NFATC2 downstream of RSPO3, leading to inhibit the non-canonical Wnt signaling pathway and promoting vessel regression. Also has ATPase activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ALK lymphoma oligomerization partner on chromosome 17; E3 ubiquitin-lipopolysaccharide ligase RNF213; E3 ubiquitin-protein ligase RNF213; Mysterin; RING finger protein 213
Gene Aliases: ALO17; C17orf27; KIAA1554; KIAA1618; MYMY2; MYSTR; NET57; RNF213
UniProt ID: (Human) Q63HN8
Entrez Gene ID: (Human) 57674
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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