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Invitrogen
SMARCC1 Polyclonal Antibody
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Product Details
PA5-55441
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human SMARCC1. Recombinant protein control fragment (Product #RP-89406).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: AHVKKVQEAA RASGKVDPTY GLESSCIAGT GPDEPEKLEG AEEEKMEADP DGQQPEKAEN KVENETDEGD KAQDGENEKN SEKEQDSEVS EDTKSEEKET EENKELTDTC KERESDTGKK KVEHEISEGN VATAAAAALA SAATKAKHL
Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 93%.
Target Information
The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and contains a predicted leucine zipper motif typical of many transcription factors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BAF155; BRG1-associated factor 155; chromatin remodeling complex BAF155 subunit; mammalian chromatin remodeling complex BRG1-associated factor 155; SWI/SNF complex 155 kDa subunit; SWI/SNF complex subunit SMARCC1; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1
Gene Aliases: BAF155; CRACC1; Rsc8; SMARCC1; SRG3; SWI3
UniProt ID: (Human) Q92922
Entrez Gene ID: (Human) 6599
nucleosome disassembly
chromatin remodeling
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
nervous system development
insulin receptor signaling pathway
organ morphogenesis
covalent chromatin modification
prostate gland development
negative regulation of proteasomal ubiquitin-dependent protein catabolic process
ATP-dependent chromatin remodeling
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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