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Invitrogen
AKR1A1 Polyclonal Antibody
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Product Details
PA5-55680
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human AKR1A1. Recombinant protein control fragment (Product #RP-92380).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: PDEPVLLEEP VVLALAEKYG RSPAQILLRW QVQRKVICIP KSITPSRILQ NIKVFDFTFS PEEMKQLNAL NKNWRYIVPM LTVDGKRVPR DAGHPLYPF
Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 96%.
Target Information
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member, also known as aldehyde reductase, is involved in the reduction of biogenic and xenobiotic aldehydes and is present in virtually every tissue. Multiple alternatively spliced transcript variants of this gene exist, all encoding the same protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 3-DG-reducing enzyme; AKR1A1; AKR1A1 protein; alcohol dehydrogenase; Alcohol dehydrogenase [NADP(+)]; Aldehyde reductase; aldehyde reductase (EC 1.1.1.2); Aldo-keto reductase family 1 member A1; aldo-keto reductase family 1, member A4 (aldehyde reductase); dihydrodiol dehydrogenase 3; epididymis secretory protein Li 6; epididymis secretory sperm binding protein Li 165mP; Glucuronate reductase; Glucuronolactone reductase; HEL-S-165mP; MGC12529; MGC1380; OTTHUMP00000009240; S-nitroso-CoA reductase; ScorR; unnamed protein product
Gene Aliases: 2610201A18Rik; AKR1A1; Akr1a4; ALDR1; ALR; ARM; DD3; HEL-S-6
UniProt ID: (Human) P14550, (Rat) P51635, (Mouse) Q9JII6
Entrez Gene ID: (Human) 10327, (Rat) 78959, (Mouse) 58810
alditol:NADP+ 1-oxidoreductase activity
retinol dehydrogenase activity
protein binding
alcohol dehydrogenase (NADP+) activity
oxidoreductase activity
allyl-alcohol dehydrogenase activity
L-glucuronate reductase activity
glucuronolactone reductase activity
glycerol dehydrogenase (NADP+) activity
S-nitrosoglutathione reductase activity
S-nitrosoglutathione reductase (NADPH) activity
methylglyoxal reductase (NADPH) (acetol producing) activity
molecular_function
oxidoreductase
reductase
metabolite interconversion enzyme
lipid metabolic process
glucuronate catabolic process to xylulose 5-phosphate
D-glucuronate catabolic process
negative regulation of apoptotic process
daunorubicin metabolic process
doxorubicin metabolic process
aldehyde catabolic process
cellular detoxification of aldehyde
glutathione derivative biosynthetic process
biological_process
L-ascorbic acid biosynthetic process
oxidation-reduction process
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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