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Invitrogen
C1orf77 Polyclonal Antibody
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Product Details
PA5-55929
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
C. elegans
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human C1orf77. Recombinant protein control fragment (Product #RP-94351).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: GRGRGMIGRG RGGFGGRGRG RGRGRGALAR PVLTKEQLDN QLDAYMSKTK GHLDAELDAY MAQTDPETND
Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.
Target Information
CHTOP is a small nuclear protein that is characterized by an arginine and glycine rich region. This protein may have an important role in the regulation of fetal globin gene expression and in the activation of estrogen-responsive genes. A recent study reported that this protein binds 5-hydroxymethylcytosine (5hmC) and associates with an arginine methyltransferase complex (methylosome), which promotes methylation of arginine 3 of histone H4 (H4R3) and activation of genes involved in glioblastomagenesis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Chromatin target of PRMT1 protein; DKFZP547E1010; Friend of Prmt1; Friend of PRMT1 protein; RP1-178F15.2; Small arginine- and glycine-rich protein; small protein rich in arginine and glycine; SRAG
Gene Aliases: C1orf77; CHTOP; FL-SRAG; FOP; HT031; PP7704; SRAG; SRAG-3; SRAG-5
UniProt ID: (Human) Q9Y3Y2
Entrez Gene ID: (Human) 26097
regulation of transcription, DNA-templated
termination of RNA polymerase II transcription
RNA export from nucleus
mRNA export from nucleus
positive regulation of cell proliferation
positive regulation of histone methylation
mRNA 3'-end processing
positive regulation of ATPase activity
positive regulation of helicase activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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