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Invitrogen
TAF4B Polyclonal Antibody
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Product Details
PA5-56014
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human TAF4B. Recombinant protein control fragment (Product #RP-89354).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: PHLVPFLKKS VVALRQLLPN SQSFIQQCVQ QTSSDMVIAT CTTTVTTSPV VTTTVSSSQS EKSIIVSGAT APRTVSVQTL NPLAGPVGAK AGVVTLHSVG PTAATGGTTA GTGLLQTSKP LVTSVANTVT TVSLQPEKPV VSGTAVT
Highest antigen sequence identity to the following orthologs: Mouse - 74%, Rat - 70%.
Target Information
TAF II p105, also called TAF4B, is a celltype specific transcriptional co-activator that is a component of the TFIID complex. Expressed primarily in B cells and ovarian granulosa cells, TAF II p105 can interact with OCBA/POU2AF1 to activate B cell-specific octamerdependent transcription. Additionally, TAF II p105 plays an important role in co-activating the transcription factor NFkB and is essential for activation of anti-apoptotic genes such as TNFAIP3. TAF II p135, also known as TAF4, TAF2C, TAF2C1, TAF4A or TAFII130, is a 1,085 amino acid subunit of TFIID that accelerates transcriptional activation triggered by thyroid hormone (TR) or retinoic acid (RA). Localized to the nucleus, TAF II p135 contains one TAFH domain and is thought to bind to proteins that contain glutamine-rich domains, such as the transcription factor CREB.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: TAF(II)105; TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa; TAFII-105; TATA box binding protein (TBP)-associated factor 4B; TATA box binding protein (TBP)-associated factor, RNA polymerase II, C2, 105kD; TATA box binding protein associated factor 4b; Transcription initiation factor TFIID 105 kDa subunit; Transcription initiation factor TFIID subunit 4B
Gene Aliases: SPGF13; TAF2C2; TAF4B; TAFII105
UniProt ID: (Human) Q92750
Entrez Gene ID: (Human) 6875
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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