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Invitrogen
KV4.3 (KCND3) Polyclonal Antibody
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Product Details
PA5-56151
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human KCND3. Recombinant protein control fragment (Product #RP-91276).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: NYPSTRSPSL SSHPGLTTTC CSRRSKKTTH LPNSNLPATR LRSMQELSTI HIQGSEQPSL TTSRSSLNLK ADDGLRPNCK TSQITTAIIS IPTPPALTPE GESRPPPASP GPNTNIPSIA SNVVKVS
Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 98%.
Target Information
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member includes two isoforms with different sizes, which are encoded by alternatively spliced transcript variants of this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: A-type voltage-gated potassium channel KCND3; potassium channel, voltage gated Shal related subfamily D, member 3; potassium ionic channel Kv4.3; potassium voltage-gated channel long; Potassium voltage-gated channel subfamily D member 3; potassium voltage-gated channel, Shal-related subfamily, member 3; sha1-related potassium channel Kv4.3; voltage-gated K+ channel; Voltage-gated potassium channel subunit Kv4.3
Gene Aliases: BRGDA9; KCND3; KCND3L; KCND3S; KSHIVB; KV4.3; SCA19; SCA22
UniProt ID: (Human) Q9UH86
Entrez Gene ID: (Human) 3752
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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