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Invitrogen
PCSK5 Polyclonal Antibody
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Product Details
PA5-56631
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human PCSK5. Recombinant protein control fragment (Product #RP-89239).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: YLEHVVVRIT ITHPRRGDLA IYLTSPSGTR SQLLANRLFD HSMEGFKNWE FMTIHCWGER AAGDWVLEVY DTPSQLRNFK TPGKLKEWSL VLYGTSVQPY SPTNEFPKVE RFRYSRVEDP TDD
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.
Target Information
PCSK5 belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. PCSK5 mediates posttranslational endoproteolytic processing for several integrin alpha subunits. It is thought to process prorenin, pro-membrane type-1 matrix metalloproteinase and HIV-1 glycoprotein gp160. Two alternatively spliced transcripts are described for this gene but only one has its full length nature known. The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein mediates posttranslational endoproteolytic processing for several integrin alpha subunits. It is thought to process prorenin, pro-membrane type-1 matrix metalloproteinase and HIV-1 glycoprotein gp160. Two alternatively spliced transcripts are described for this gene but only one has its full length nature known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: PC5; PC6; prohormone convertase 5; Proprotein convertase 5; Proprotein convertase 6; Proprotein convertase subtilisin/kexin type 5; protease PC6; subtilase; Subtilisin/kexin-like protease PC5
Gene Aliases: PC5; PC6; PC6A; PCSK5; SPC6
UniProt ID: (Human) Q92824
Entrez Gene ID: (Human) 5125
kidney development
renin secretion into blood stream
cardiac septum development
signal peptide processing
cell-cell signaling
determination of left/right symmetry
heart development
embryo implantation
anterior/posterior pattern specification
protein processing
peptide hormone processing
viral life cycle
respiratory tube development
nerve growth factor processing
limb morphogenesis
cytokine biosynthetic process
peptide biosynthetic process
embryonic digestive tract development
embryonic skeletal system development
coronary vasculature development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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