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Invitrogen
proCNP Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-57241
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human CNP. Recombinant protein control fragment (Product #RP-95804).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.3 mg/mL
Amount
30 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: PKVPRTPPAE ELAEPQAAGG GQKKGDKAPG GGGANLKGDR SRLLRDLRVD TKSRAAWARL LQEHPNARKY KGANKKGLSK GCFGLKLDRI GSMSGLGC
Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 95%.
Target Information
Natriuretic peptides comprise a family of 3 structurally related molecules: atrial natriuretic peptide (ANP; MIM 108780), brain natriuretic peptide (BNP; MIM 600295), and C-type natriuretic peptide, CNP, encoded by a gene symbolized NPPC. These peptides possess potent natriuretic, diuretic, and vasodilating activities and are implicated in body fluid homeostasis and blood pressure control.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: natriuretic peptide precursor type C
Gene Aliases: CNP; CNP2
UniProt ID: (Human) P23582
Entrez Gene ID: (Human) 4880
angiogenesis
ovarian follicle development
cumulus cell differentiation
response to hypoxia
blood vessel remodeling
response to ischemia
growth plate cartilage chondrocyte differentiation
growth plate cartilage chondrocyte proliferation
cGMP biosynthetic process
protein folding
cellular calcium ion homeostasis
receptor guanylyl cyclase signaling pathway
negative regulation of cell proliferation
response to xenobiotic stimulus
response to wounding
negative regulation of collagen biosynthetic process
gastric emptying
response to decreased oxygen levels
negative regulation of neuron apoptotic process
response to ethanol
positive regulation of osteoblast differentiation
oocyte development
regulation of smooth muscle cell proliferation
response to axon injury
chromosome organization
negative regulation of meiotic cell cycle
c-di-GMP signaling
multicellular organismal locomotion
response to oxygen-glucose deprivation
negative regulation of oocyte maturation
meiotic cell cycle process involved in oocyte maturation
cellular response to glycoprotein
negative regulation of DNA biosynthetic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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