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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: GVQHTDKRKK KGRKIPKLEE LLSKRDFTGA ITLLEFKRHV GEEEEDTNLW IGYCAFHLGD YKRALEEYEN ATKEENCNSE VWVNLACTYF FLGMYKQAEA AGFKASKSRL QNRLLFHLAH
Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 93%.
Component of the intraflagellar transport (IFT) complex B required for transport of proteins in the motile cilium. Required for transport of specific ciliary cargo proteins related to motility, while it is neither required for IFT complex B assembly or motion nor for cilium assembly. Required for efficient coupling between the accumulation of GLI2 and GLI3 at the ciliary tips and their dissociation from the negative regulator SUFU. Plays a key role in maintaining the integrity of the IFT complex B and the proper ciliary localization of the IFT complex B components. Not required for IFT complex A ciliary localization or function. Essential for maintaining proper microtubule organization within the ciliary axoneme. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: tetratricopeptide repeat domain 26; tetratricopeptide repeat protein 26; TPR repeat protein 26; unnamed protein product
Gene Aliases: BRENS; dyf-13; DYF13; TTC26
UniProt ID: (Human) A0AVF1
Entrez Gene ID: (Human) 79989
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