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Invitrogen
POLR3B Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-57671
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human POLR3B. Recombinant protein control fragment (Product #RP-97632).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: VEADRKGAVG ASVTSSTHEK KSRTNMAVKQ GRFYLRHNTL SEDIPIVIIF KAMGVESDQE IVQMIGTEEH VMAAFGPSLE ECQKAQIFTQ MQ
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.
Target Information
POLR3B (RNA Polymerase III Subunit B) is a Protein Coding gene. Diseases associated with POLR3B include Leukodystrophy, Hypomyelinating, 8, With Or Without Oligodontia And/Or Hypogonadotropic Hypogonadism and Cerebellar Hypoplasia With Endosteal Sclerosis. Among its related pathways are RNA Polymerase II Transcription Initiation And Promoter Clearance and ATP/ITP metabolism. Gene Ontology (GO) annotations related to this gene include DNA-directed 5'-3' RNA polymerase activity and ribonucleoside binding. An important paralog of this gene is POLR2B.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DNA-directed RNA polymerase III 127.6 kDa polypeptide; DNA-directed RNA polymerase III subunit B; FLJ10388; interphase nucleus and mitotic apparatus associated protein; polymerase (RNA) III (DNA directed) polypeptide B; polymerase (RNA) III subunit B; RNA polymerase III subunit C2; unnamed protein product
Gene Aliases: C128; CMT1I; HLD8; INMAP; RPC2
UniProt ID: (Human) Q9NW08
Entrez Gene ID: (Human) 55703
transcription, DNA-templated
DNA-templated transcription, elongation
transcription from RNA polymerase III promoter
transcription initiation from RNA polymerase III promoter
termination of RNA polymerase III transcription
positive regulation of interferon-beta production
snRNA transcription from RNA polymerase III promoter
positive regulation of innate immune response
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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