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Invitrogen
PPP2R5B Polyclonal Antibody
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Product Details
PA5-57740
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human PPP2R5B. Recombinant protein control fragment (Product #RP-97258).
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: GKLFDELTAS YKLEKQQEQQ KAQERQELWQ GLEELRLRRL QGTQGAKEAP LQRLTP
Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 93%.
Target Information
This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes a beta isoform of the catalytic subunit. Two transcript variants encoding the same protein have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ35411; PP2A; PP2A B subunit isoform B'-beta; PP2A B subunit isoform B56-beta; PP2A B subunit isoform PR61-beta; PP2A B subunit isoform R5-beta; protein phosphatase 2 regulatory subunit B', beta; protein phosphatase 2, regulatory subunit B (B56), beta isoform; protein phosphatase 2, regulatory subunit B', beta isoform; serine/threonine protein phosphatase 2A, 56 kDa regulatory subunit, beta isoform; Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform
Gene Aliases: B'beta; B56B; BC026670; LOC100909468; PPP2R5B; PR61B; rCG_47223
UniProt ID: (Human) Q15173, (Mouse) Q6PD28, (Rat) Q80W83
Entrez Gene ID: (Human) 5526, (Mouse) 225849, (Rat) 309179
regulation of receptor activity
positive regulation of neuron projection development
regulation of phosphatidylinositol 3-kinase signaling
positive regulation of protein complex assembly
regulation of protein autophosphorylation
regulation of protein phosphatase type 2A activity
IRE1-mediated unfolded protein response
positive regulation of transcription from RNA polymerase II promoter
regulation of peptidyl-tyrosine phosphorylation
positive regulation of sequence-specific DNA binding transcription factor activity
positive regulation of neurotrophin TRK receptor signaling pathway
negative regulation of G0 to G1 transition
positive regulation of cell cycle arrest
cellular response to growth factor stimulus
regulation of protein phosphorylation
signal transduction
regulation of catalytic activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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