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Invitrogen
SPA17 Polyclonal Antibody
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Product Details
PA5-58013
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human SPA17. Recombinant protein control fragment (Product #RP-97273).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: EQPDNIPAFA AAYFESLLEK REKTNFDPAE WGSKVEDRFY NNHAFEEQEP PEKSDPKQEE SQISGKEEET SVTILDSSEE DKEKEEVAAV K
Highest antigen sequence identity to the following orthologs: Mouse - 68%, Rat - 67%.
Target Information
This gene encodes a protein present at the cell surface. The N-terminus has sequence similarity to human cAMP-dependent protein kinase A (PKA) type II alpha regulatory subunit (RIIa) while the C-terminus has an IQ calmodulin-binding motif. The central portion of the protein has carbohydrate binding motifs and likely functions in cell-cell adhesion. The protein was initially characterized by its involvement in the binding of sperm to the zona pellucida of the oocyte. Recent studies indicate that it is also involved in additional cell-cell adhesion functions such as immune cell migration and metastasis. A retrotransposed pseudogene is present on chromosome 10q22.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Cancer/testis antigen 22; CT22; Sp17; Sp17-1; Sperm autoantigenic protein 17; Sperm protein 17; Sperm surface protein Sp17; unnamed protein product
Gene Aliases: CT22; SP17; SP17-1; SPA17
UniProt ID: (Human) Q15506
Entrez Gene ID: (Human) 53340
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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