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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: KGTGKERPGL IEFEECDTAS AVEGIKPRKR KTFALPGIIK KEKDAESVEC PDADSLNIPD VDEEGYSI
Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 97%.
FCHO2 (FCH domain only 2) is a ubiquitously expressed member of the FCFBS superfamily characterized by FES-CIP4 homology (FCH) domain, an FBH domain, and an SH3 domain. Both FCHO2 and the related protein FCHO1 are mediators of clathrin-mediated endocytosis, acting to sculpt the initial bud site and recruit the clathrin machinery for clathrin-coated vesicle formation. FCHO2 binds to Eps15, an important adaptor protein in clathrin-mediated endocytosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: FCH domain only 2; FCH domain only protein 2; unnamed protein product
UniProt ID: (Human) Q0JRZ9
Entrez Gene ID: (Human) 115548
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