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          • Primary Antibodies ›
          • MAP4 Antibodies

          Invitrogen

          MAP4 Polyclonal Antibody

          Advanced Verification
          View all (9) MAP4 antibodies

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          Cite MAP4 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (6)
          • Advanced Verification (1)
          MAP4 Antibody in Immunocytochemistry (ICC/IF)
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          MAP4 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 7

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          MAP4 Antibody (PA5-58273) in ICC/IF

          Immunofluorecent analysis of MAP4 in human cell line U-2 OS using MAP4 Polyclonal Antibody (Product # PA5-58273). Staining shows localization to plasma membrane, cytosol and microtubules. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
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          View Product

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          MAP4 Antibody in Immunocytochemistry (ICC/IF)
          MAP4 Antibody in Immunohistochemistry (IHC)
          MAP4 Antibody in Immunohistochemistry (IHC)
          MAP4 Antibody in Immunohistochemistry (IHC)
          MAP4 Antibody in Immunohistochemistry (IHC)
          MAP4 Antibody in Immunohistochemistry (IHC)
          MAP4 Antibody
          MAP4 Polyclonal Antibody

          Product Details

          PA5-58273

          Applications
          Tested Dilution
          Publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:2,500-1:5,000
          -

          Immunocytochemistry (ICC/IF)

          0.25-2 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human MAP4. Recombinant protein control fragment (Product #RP-96263).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.1 mg/mL

          Amount

          10 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2643742

          Product Specific Information

          Immunogen sequence: PPAQALEIMM GLKTTDMAPS KETEMALAKD MALATKTEVA LAKDMESPTK LDVTLAKDMQ PSMESDMALV KDMELPTEKE VALVKDVRWP TETDVSSAKN VV

          Highest antigen sequence identity to the following orthologs: Mouse - 48%, Rat - 47%.

          Target Information

          The protein encoded by this gene is a major non-neuronal microtubule-associated protein. This protein contains a domain similar to the microtubule-binding domains of neuronal microtubule-associated protein (MAP2) and microtubule-associated protein tau (MAPT/TAU). This protein promotes microtubule assembly, and has been shown to counteract destabilization of interphase microtubule catastrophe promotion. Cyclin B was found to interact with this protein, which targets cell division cycle 2 (CDC2) kinase to microtubules. The phosphorylation of this protein affects microtubule properties and cell cycle progression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: MAP-4; Microtubule-associated protein 4; unnamed protein product

          View more View less

          Gene Aliases: MAP4

          View more View less

          UniProt ID: (Human) P27816

          View more View less

          Entrez Gene ID: (Human) 4134

          View more View less

          Function(s)
          RNA binding structural molecule activity protein binding microtubule binding tubulin binding microtubule stabilizing activity
          Process(es)
          microtubule cytoskeleton organization mitotic spindle organization neuron projection development microtubule polymerization microtubule sliding establishment of spindle orientation cell division cilium disassembly negative regulation of nonmotile primary cilium assembly
          It has to be done as per old AB suggested Products section.

          Disclaimer

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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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