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Invitrogen
RDH16 Polyclonal Antibody
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Product Details
PA5-58423
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human RDH16. Recombinant protein control fragment (Product #RP-97767).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: GVKVAMIEPG YFKTAVTSKE RFLKSFLEIW DRSSPEVKEA YGEKFVADYK KSAEQMEQKC TQDLSLVT
Highest antigen sequence identity to the following orthologs: Mouse - 54%, Rat - 54%.
Target Information
Retinol dehydrogenase 16 (RDH16) is an oxidoreductase with a preference for NAD. It oxidizes all-trans-retinol and 13-cis-retinol to the corresponding aldehydes. RDH16 has higher activity towards CRBP-bound retinol than with free retinol. It oxidizes 3-alpha-hydroxysteroids and also oxidizes androstanediol and androsterone to dihydrotestosterone and androstanedione. RDH16 can also catalyze the reverse reaction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: hRDH-E; Human epidermal retinol dehydrogenase; Microsomal NAD(+)-dependent retinol dehydrogenase 4; microsomal NAD+-dependent retinol dehydrogenase 4; RDHE; Retinol dehydrogenase 16; retinol dehydrogenase 16 (all-trans and 13-cis); retinol dehydrogenase 16 (all-trans); RoDH-4; Short chain dehydrogenase/reductase family 9C member 8; short chain dehydrogenase/reductase family 9C, member 8; Sterol/retinol dehydrogenase
Gene Aliases: hRDH-E; RDH16; RODH-4; RODH4; SDR9C8
UniProt ID: (Human) O75452
Entrez Gene ID: (Human) 8608
retinol dehydrogenase activity
electron carrier activity
oxidoreductase activity
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
identical protein binding
androsterone dehydrogenase activity
androstan-3-alpha,17-beta-diol dehydrogenase activity
11-cis-retinol dehydrogenase (NAD+) activity
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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