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Invitrogen
Acrosomal Vesicle Protein Polyclonal Antibody
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FIGURE: 1 / 9
Acrosomal Vesicle Protein Antibody (PA5-58512) in IHC
Immunohistochemical staining of Acrosomal Vesicle Protein in human cerebral cortex, liver, lymph node and testis using Acrosomal Vesicle Protein Polyclonal Antibody (Product # PA5-58512) (A) shows similar protein distribution across tissues to an independent Acrosomal Vesicle Protein Polyclonal Antibody (B).
Product Details
PA5-58512
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human Acrosomal Vesicle Protein. Recombinant protein control fragment (Product #RP-97353).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Amount
5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: SGEHASGEQA SGAPISSTST GTILNCYTCA YMNDQGKCLR GEGTCITQNS QQCMLKKIFE GGKLQFMVQG CENMCPSMNL FSH
Highest antigen sequence identity to the following orthologs: Mouse - 71%, Rat - 72%.
Target Information
This gene encodes a testis-specific, differentiation antigen, acrosomal vesicle protein 1, that arises within the acrosomal vesicle during spermatogenesis, and is associated with the acrosomal membranes and matrix of mature sperm. This gene consists of 4 exons and its alternative splicing generates multiple distinct transcripts, which encode protein isoforms ranging from 81 to 265 amino acids. The longest transcript is the most abundant, comprising 53-72% of the total acrosomal vesicle protein 1 messages; the second largest transcript comprises 15-32%; the third and the fourth largest transcripts account for 3.4-8.3% and 8.7-12.5%, respectively; and the remaining transcripts combined account for < 1% of the total acrosomal vesicle protein 1 message. It is suggested that phenomena of cryptic splicing and exon skipping occur within this gene. The acrosomal vesicle protein 1 may be involved in sperm-zona binding or penetration, and it is a potential contraceptive vaccine immunogen for humans.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Acrosomal protein SP-10; Acrosomal vesicle protein 1; sperm protein 10
Gene Aliases: ACRV1; D11S4365; SP-10; SPACA2
UniProt ID: (Human) P26436
Entrez Gene ID: (Human) 56
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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