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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • UNC45A Antibodies

          Invitrogen

          UNC45A Polyclonal Antibody

          View all (3) UNC45A antibodies

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          Cite UNC45A Polyclonal Antibody

          • Antibody Testing Data (6)
          UNC45A Antibody in Immunocytochemistry (ICC/IF)
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          UNC45A Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 6

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          UNC45A Antibody (PA5-58703) in ICC/IF

          Immunofluorescent staining of UNC45A in human cell line HEK 293 using an UNC45A Polyclonal Antibody (Product # PA5-58703) shows localization to cytosol and the Golgi apparatus. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
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          UNC45A Antibody in Immunocytochemistry (ICC/IF)
          UNC45A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          UNC45A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          UNC45A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          UNC45A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          UNC45A Antibody in Western Blot (WB)
          UNC45A Polyclonal Antibody

          Product Details

          PA5-58703

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          0.04-0.4 µg/mL
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:500-1:1,000
          -

          Immunocytochemistry (ICC/IF)

          0.25-2 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human UNC45A. Recombinant protein control fragment (Product #RP-98108).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2649269

          Product Specific Information

          Immunogen sequence: QELQHRGAVV VLNMVEASRE IASTLMESEM MEILSVLAKG DHSPVTRAAA ACLDKAVEYG LIQPNQDG

          Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 84%.

          Target Information

          UNC45A, also named as SMAP1, acts as co-chaperone for HSP90. UNC45A prevents the stimulation of HSP90AB1 ATPase activity by AHSA1. It is a positive factor in promoting PGR function in the cell. It is necessary for proper folding of myosin and necessary for normal cell proliferation, normal myotube formation and myosin accumulation during muscle cell development. UNC45A plays a role in erythropoiesis in stroma cells in the spleen.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Let us know so we can reference it here.
          Cite this product

          Bioinformatics

          Protein Aliases: GCUNC-45; general cell UNC45; Protein unc-45 homolog A; SMAP-1; smooth muscle cell associated protein-1; Smooth muscle cell-associated protein 1; unc-45 homolog A; Unc-45A

          View more View less

          Gene Aliases: GC-UNC45; GCUNC-45; GCUNC45; IRO039700; SMAP-1; SMAP1; UNC-45A; UNC45A

          View more View less

          UniProt ID: (Human) Q9H3U1

          View more View less

          Entrez Gene ID: (Human) 55898

          View more View less

          Function(s)
          protein binding Hsp90 protein binding cadherin binding involved in cell-cell adhesion
          Process(es)
          muscle organ development cell differentiation chaperone-mediated protein folding cell-cell adhesion
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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