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Invitrogen
ADH7 Polyclonal Antibody
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Product Details
PA5-58887
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human ADH7. Recombinant protein control fragment (Product #RP-96754).
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: KFEKAMAVGA TECISPKDST KPISEVLSEM TGNNVGYTFE VIGHLETMID ALASCHMNYG TSV
Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 81%.
Target Information
This gene encodes class IV alcohol dehydrogenase 7 mu or sigma subunit, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The enzyme encoded by this gene is inefficient in ethanol oxidation, but is the most active as a retinol dehydrogenase; thus it may participate in the synthesis of retinoic acid, a hormone important for cellular differentiation. The expression of this gene is much more abundant in stomach than liver, thus differing from the other known gene family members.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ADH-C2; alcohol dehydrogenase 3 complex; alcohol dehydrogenase 3 temporal; alcohol dehydrogenase 4; Alcohol dehydrogenase 7; Alcohol dehydrogenase class 4 mu/sigma chain; Alcohol dehydrogenase class IV mu/sigma chain; alcohol dehydrogenase VII; alcohol dehydrogenase-7; All-trans-retinol dehydrogenase [NAD(+)] ADH7; class IV alcohol dehydrogenase, mu or sigma subunit; class IV sigma-1 alcohol dehydrogenase; class IV sigmasigma alcohol dehydrogenase; Gastric alcohol dehydrogenase; IV ADH; Omega-hydroxydecanoate dehydrogenase ADH7; ret; Retinol dehydrogenase; unnamed protein product
Gene Aliases: Adh-3; Adh-3e; Adh-3t; Adh3; Adh3-e; Adh3-t; ADH4; ADH7; Adt-1; AI325182
UniProt ID: (Human) P40394, (Rat) P41682, (Mouse) Q64437
Entrez Gene ID: (Human) 131, (Rat) 171178, (Mouse) 11529
alcohol dehydrogenase (NAD) activity
aldehyde oxidase activity
retinol dehydrogenase activity
zinc ion binding
oxidoreductase activity
retinol binding
ethanol binding
metal ion binding
receptor antagonist activity
omega-hydroxydecanoate dehydrogenase activity
alcohol dehydrogenase activity, zinc-dependent
protein homodimerization activity
NAD binding
dehydrogenase
oxidoreductase
metabolite interconversion enzyme
retinoid metabolic process
lipid metabolic process
response to bacterium
fatty acid omega-oxidation
monocarboxylic acid metabolic process
retinol metabolic process
retinoic acid metabolic process
response to ethanol
ethanol metabolic process
ethanol catabolic process
ethanol oxidation
oxidation-reduction process
extracellular negative regulation of signal transduction
negative regulation of receptor activity
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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