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Invitrogen
C20orf196 Polyclonal Antibody
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Product Details
PA5-59280
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human C20orf196. Recombinant protein control fragment (Product #RP-99453).
Conjugate
Form
Liquid
Concentration
0.30 mg/mL
Amount
30 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: NNSWTAENFW LDPAVKGQSE KEEDDGLRKS LDRFYEMFGH PQPGSANSLS ASVCKCLSQK ITQLRGQES
Highest antigen sequence identity to the following orthologs: Mouse - 70%, Rat - 67%.
Target Information
Representing about 2% of human DNA, chromosome 20 consists of approximately 63 million bases and 600 genes. Chromosome 20 contains a region with numerous genes expressed in the epididymis, which are thought important for seminal production, and some viewed as potential targets for male contraception. The PRNP gene encoding the prion protein associated with spongiform encephalopathies, like Creutzfeldt-Jakob disease, is found on chromosome 20. Amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome are also associated with chromosome 20.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: RINN1-REV7-interacting novel NHEJ regulator 3; Shield complex subunit 1; Shieldin complex subunit 1; uncharacterized protein C20orf196; unnamed protein product
Gene Aliases: C20orf196; RINN3; SHLD1
UniProt ID: (Human) Q8IYI0
Entrez Gene ID: (Human) 149840
somatic diversification of immunoglobulins involved in immune response
DNA repair
cellular response to DNA damage stimulus
telomere maintenance in response to DNA damage
positive regulation of isotype switching
negative regulation of double-strand break repair via homologous recombination
regulation of double-strand break repair via nonhomologous end joining
positive regulation of double-strand break repair via nonhomologous end joining
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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