Invitrogen

Naked1 Polyclonal Antibody

View all (8) Naked1 antibodies

Questions & Answers

Questions & Answers

Questions & Answers

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Antibody Testing Data (1)

Naked1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Naked1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 1

Naked1 Antibody (PA5-59529) in IHC (P)

Immunohistochemical analysis of Naked1 in human smooth muscle using Naked1 Polyclonal Antibody (Product # PA5-59529) shows moderate cytoplasmic positivity in smooth muscle cells.

Naked1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Product Image Gallery

Naked1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemical analysis of Naked1 in human smooth muscle using Naked1 Polyclonal Antibody (Product # PA5-59529) shows moderate cytoplasmic positivity in smooth muscle cells.

Immunogen image

Naked1 Polyclonal Antibody

Immunogen Image Naked1 Polyclonal Antibody

Product Details

PA5-59529

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human Naked1. Recombinant protein control fragment (Product #RP-98725).

3D Epitope / Immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

10 µg

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Immunogen sequence: WARKGIEEWI GRQRCPGGVS GPRQLRLAGT IGRSTRELVG DVLRDTLSEE EEDDFRLEVA LPPEKTDGLG SGDEKKMERV SEPCP

Highest antigen sequence identity to the following orthologs: Mouse - 81%, Rat - 78%.

Target Information

In the mouse, Nkd is a Dishevelled (see DVL1; MIM 601365)-binding protein that functions as a negative regulator of the Wnt (see WNT1; MIM 164820)-beta-catenin-Tcf signaling pathway.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Dvl-binding protein; HNKD; hNkd1; naked cuticle homolog 1; naked cuticle-1; Naked-1; NKD1, WNT signaling pathway inhibitor; Protein naked cuticle homolog 1; unnamed protein product

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Gene Aliases: Naked1; NKD; NKD1; PP7246

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UniProt ID: (Human) Q969G9

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Entrez Gene ID: (Human) 85407

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calcium ion binding protein binding PDZ domain binding metal ion binding

eye photoreceptor cell differentiation axis elongation somatic muscle development Wnt signaling pathway negative regulation of Wnt signaling pathway positive regulation of MAPK cascade positive regulation of protein catabolic process convergent extension negative regulation of canonical Wnt signaling pathway regulation of cell motility involved in somitogenic axis elongation positive regulation of non-canonical Wnt signaling pathway positive regulation of Wnt signaling pathway, planar cell polarity pathway

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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