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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: APRLQSEVAE LKIVADQLCA KYSKEYGKLC RTNQIGTVND RLMHKLSVEA PPKILVERYL IEIAKNYNVP YEPDSVVMAE APPGVETDLI DVGFTDD
Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.
Proposed to be involved in specific functions of the ESCRT machinery. Is required for efficient abscission during cytokinesis, but not for HIV-1 budding. The involvement in the MVB pathway is not established. Involved in recruiting VPS4A and/or VPS4B to the midbody of dividing cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Charged multivesicular body protein 8; CHMP8; hIST1; IST1 homolog; MGC117220; pm28; Putative MAPK-activating protein PM28
Gene Aliases: IST1; KIAA0174
Entrez Gene ID: (Human) 9798
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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