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          • Primary Antibodies ›
          • CHCHD3 Antibodies

          Invitrogen

          CHCHD3 Polyclonal Antibody

          Advanced Verification
          View all (13) CHCHD3 antibodies

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          Cite CHCHD3 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (8)
          • Advanced Verification (1)
          CHCHD3 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          CHCHD3 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 9

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          CHCHD3 Antibody (PA5-60167) in ICC/IF

          Immunofluorecent analysis of CHCHD3 in human cell line U-2 OS using CHCHD3 Polyclonal Antibody (Product # PA5-60167). Staining shows localization to mitochondria. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
          PMID: {{$ctrl.currentElement.benchSciPubmedId}}
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          CHCHD3 Antibody in Immunocytochemistry (ICC/IF)
          CHCHD3 Antibody in Immunohistochemistry (IHC)
          CHCHD3 Antibody in Immunohistochemistry (IHC)
          CHCHD3 Antibody in Immunohistochemistry (IHC)
          CHCHD3 Antibody in Immunohistochemistry (IHC)
          CHCHD3 Antibody in Western Blot (WB)
          CHCHD3 Antibody in Western Blot (WB)
          CHCHD3 Antibody in Western Blot (WB)
          CHCHD3 Antibody
          CHCHD3 Polyclonal Antibody

          Product Details

          PA5-60167

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          0.04-0.4 µg/mL
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:500-1:1,000
          -

          Immunocytochemistry (ICC/IF)

          0.25-2 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human CHCHD3. Recombinant protein control fragment (Product #RP-92682).
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.5 mg/mL

          Amount

          50 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2639750

          Product Specific Information

          Immunogen sequence: DENENITVVK GIRLSENVID RMKESSPSGS KSQRYSGAYG ASVSDEELKR RVAEELALEQ AKKESEDQKR LKQAK

          Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 91%.

          Target Information

          Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Has also been shown to function as a transcription factor which binds to the BAG1 promoter and represses BAG1 transcription. Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: Coiled-coil-helix-coiled-coil-helix domain-containing protein 3; coiled-coil-helix-coiled-coil-helix domain-containing protein 3, mitochondrial; FLJ20420; MICOS complex subunit MIC19; mitochondrial contact site and cristae organizing system subunit 19; mitochondrial inner membrane organizing system 3; protein phosphatase 1, regulatory subunit 22; unnamed protein product

          View more View less

          Gene Aliases: 0610041L09Rik; 1700039J09Rik; AW558177; CHCHD3; MIC19; MICOS19; MINOS3; PPP1R22

          View more View less

          UniProt ID: (Human) Q9NX63, (Mouse) Q9CRB9

          View more View less

          Entrez Gene ID: (Human) 54927, (Rat) 296966, (Mouse) 66075

          View more View less

          Function(s)
          protein binding phosphatase binding binding, bridging transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding protein complex scaffold
          Process(es)
          negative regulation of transcription from RNA polymerase II promoter inner mitochondrial membrane organization mitochondrial fusion transcription, DNA-templated regulation of transcription, DNA-templated transcription from RNA polymerase II promoter cristae formation
          It has to be done as per old AB suggested Products section.

          Disclaimer

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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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