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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • COPE Antibodies

          Invitrogen

          COPE Polyclonal Antibody

          View all (8) COPE antibodies

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          Cite COPE Polyclonal Antibody

          • Antibody Testing Data (6)
          COPE Antibody in Immunocytochemistry (ICC/IF)
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          COPE Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 6

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          COPE Antibody (PA5-60425) in ICC/IF

          Immunofluorecent analysis of COPE in human cell line U-251 MG using COPE Polyclonal Antibody (Product # PA5-60425). Staining shows localization to the Golgi apparatus. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          COPE Antibody in Immunocytochemistry (ICC/IF)
          COPE Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          COPE Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          COPE Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          COPE Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          COPE Antibody in Western Blot (WB)
          COPE Polyclonal Antibody

          Product Details

          PA5-60425

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          0.04-0.4 µg/mL
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:200
          -

          Immunocytochemistry (ICC/IF)

          0.25-2 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human COPE. Recombinant protein control fragment (Product #RP-102946).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.05 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2640059

          Product Specific Information

          Immunogen sequence: GSGEVDELFD VKNAFYIGSY QQCINEAQRV KLSSPERDVE RDVFLYRAYL AQRKFGVVLD EIKPSSAPEL QAVRMFADYL

          Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 95%.

          Target Information

          The product of this gene is an epsilon subunit of coatomer protein complex. Coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles. It is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Coatomer complex consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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          Cite this product

          Bioinformatics

          Protein Aliases: coatomer epsilon subunit; coatomer protein complex, subunit epsilon; Coatomer subunit epsilon; epsilon coat protein; Epsilon-coat protein; Epsilon-COP

          View more View less

          Gene Aliases: COPE; epsilon-COP

          View more View less

          UniProt ID: (Human) O14579

          View more View less

          Entrez Gene ID: (Human) 11316

          View more View less

          Function(s)
          structural molecule activity protein binding membrane traffic protein vesicle coat protein
          Process(es)
          ER to Golgi vesicle-mediated transport retrograde vesicle-mediated transport, Golgi to ER intra-Golgi vesicle-mediated transport protein transport
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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