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Invitrogen
RNPS1 Polyclonal Antibody
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Product Details
PA5-60589
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human RNPS1. Recombinant protein control fragment (Product #RP-98811).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: KKSLLGVKEN NKKSSTRAPS PTKRKDRSDE KSKDRSKDKG ATKESSEKDR GRDKTRKRRS ASSG
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 98%.
Target Information
This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. This protein contains many serine residues. Two splice variants have been found for this gene; both variants encode the same protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: RNA binding protein S1, serine-rich domain; RNA binding protein with serine-rich domain; RNA-binding protein S1, serine-rich domain; RNA-binding protein with serine-rich domain 1; SR protein; SR-related protein LDC2
Gene Aliases: E5.1; LDC2; RNPS1
UniProt ID: (Human) Q15287
Entrez Gene ID: (Human) 10921
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
regulation of alternative mRNA splicing, via spliceosome
mRNA splicing, via spliceosome
transcription, DNA-templated
termination of RNA polymerase II transcription
RNA export from nucleus
mRNA export from nucleus
RNA splicing
mRNA 3'-end processing
positive regulation of apoptotic process
negative regulation of mRNA splicing, via spliceosome
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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