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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: RVDNITQISA QLSWLPTNSN YSHVIFLNEE EFDIVKAARY KYQFFNLRPN MAYKVKVLAK PHQMPWQLPL EQREKKEAFV EFSTLP
Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 95%.
The presynaptic active zone mediates synaptic vesicle exocytosis at a synapse. RIM proteins are active zone scaffolding molecules that--among others--mediate vesicle priming and directly or indirectly interact with most other essential presynaptic proteins. RIMBP2 encodes RIMS-binding protein 2 belonging to RIMBP family. RIMBP2 is supposed to be localized at cell membrane especially synaptic plasma membrane. By interacting with RIMS1, RIMS2, CACNA1D and CACNA1B via the SH3 domains, RIMBP2 mediates synaptic transmission as bifunctional linker.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: RIM-BP2; RIMS-binding protein 2
Gene Aliases: KIAA0318; RBP2; RIMBP2
Entrez Gene ID: (Human) 23504
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