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Invitrogen
GNPNAT1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-60788
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human GNPNAT1. Recombinant protein control fragment (Product #RP-88921).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.05 mg/mL
Amount
5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: TPMFDPSLLK EVDWSQNTAT FSPAISPTHP GEGLVLRPLC TADLNRGFFK VLGQLTETGV VSPEQFMKSF EHMKKSGDYY VTVVEDVTLG QIVATATLII EHKFIHSCAK RGRVEDVVVS DECRGKQLGK LLLSTLTLLS KKLNCYKITL ECLPQNVGFY KKFGYTVSEE NYMCRR
Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 98%.
Target Information
Glucosamine-6 phosphate-N-acetyl Transferase (GNPNAT1) is a key enzyme in the hexosamine biosynthetic pathway. It converts D-glucosamine 6-phosphate to N-acetyl-D-glucosamine 6-phosphate, the acetylation step allowing carbon and nitrogen enter into the hexosamine biosynthetic pathway. Recently inhibition of GNPNAT1 has been reported to promote proliferation and aggressiveness of castration-resistant prostate cancer. (27194471).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: glucosamine-6-phosphate acetyltransferase; glucosamine-phosphate N-acetyltransferase 1; glucosamine-6-phosphate acetyltransferase; glucosamine-phosphate N-acetyltransferase; phosphoglucosamine acetylase; phosphoglucosamine transacetylase; unnamed protein product
Gene Aliases: EMeg32; GNA1; GNPNAT; Gpnat1; Gsnpat; RGD1563144; RHZDAN
UniProt ID: (Human) Q96EK6, (Mouse) Q9JK38
Entrez Gene ID: (Human) 64841, (Rat) 498486, (Mouse) 54342
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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