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Invitrogen
TRF4-1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-61017
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human TRF4-1. Recombinant protein control fragment (Product #RP-96868).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: PNPLSSPHLY HKQHNGMKLS MKGSHGHTQG GGYSSVGSGG VRPPVGNRGH HQYNRTGWRR KKHTHTRDSL PVSLSR
Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 95%.
Target Information
TRF4-1 is a nuclear protein whose expression is cell cycle-regulated at a post-transcriptional level. Two genes, TRF4-1 and TRF4-2, belonging to this family have been identified. TRF4 is also required to maintain a different aspect of higher order chromosome structure, sister chromatid cohesion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DNA polymerase kappa; DNA polymerase sigma; non-canonical poly(A) polymerase; non-canonical poly(A) RNA polymerase PAPD7; PAP-associated domain-containing protein 7; poly(A) RNA polymerase D7, non-canonical; polymerase (DNA directed) sigma; terminal guanylyltransferase; terminal uridylyltransferase 5; topoisomerase-related function protein 4-1; TRAMP-like complex polyadenylate polymerase; Trf4-1p; unnamed protein product
Gene Aliases: LAK-1; LAK1; PAPD7; POLK; POLS; TRF4; TRF4-1; TRF41; TUTASE5
UniProt ID: (Human) Q5XG87
Entrez Gene ID: (Human) 11044
double-strand break repair
RNA catabolic process
sister chromatid cohesion
mitotic chromosome condensation
response to xenobiotic stimulus
RNA 3'-end processing
polyadenylation-dependent ncRNA catabolic process
negative regulation of nuclear-transcribed mRNA poly(A) tail shortening
positive regulation of 3'-UTR-mediated mRNA stabilization
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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