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Immunogen sequence: QASKNIIQPP SCVLHYYNVP LCVTEETFTK LCNDHEVLTF IKYKVFDAKP SAKTLSGLLE WECKTD
Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 95%.
HNRNPLL is a master regulator of activation-induced alternative splicing in T cells. In particular, it alters splicing of CD45 (PTPRC), a tyrosine phosphatase essential for T-cell development and activation (Oberdoerffer et al., 2008).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Heterogeneous nuclear ribonucleoprotein L-like; hnRNPLL; stromal RNA regulating factor; Stromal RNA-regulating factor
Gene Aliases: BLOCK24; HNRNPLL; HNRPLL; SRRF
UniProt ID: (Human) Q8WVV9
Entrez Gene ID: (Human) 92906
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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