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Invitrogen
IGSF11 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-61231
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human IGSF11. Recombinant protein control fragment (Product #RP-98480).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: PPKCSSAKAF HTEISSSDNN TLTSSNAYNS RYWSNNPKVH RNTESVSHFS DLGQSFSFHS GNANIPSIYA NGTHLVPGQH KTLVVTANRG SSPQVMSRSN GSVSRKP
Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 84%.
Target Information
Immunoglobulin superfamily member 11 (IGSF11) is a gene located on chromosome 3q13.3, encoding a transmembrane protein that belongs to the immunoglobulin superfamily. IGSF11 is known for its expression in the brain, where it plays a role in neuron-to-neuron adhesion and synaptic organization. The protein is involved in processes such as synapse formation and stabilization, impacting neural connectivity and signaling pathways. IGSF11 is also expressed in other tissues, including the gastrointestinal tract, where it can contribute to cell adhesion functions. Research has linked IGSF11 to cancer biology, as its expression is altered in various cancers, potentially influencing tumor cell adhesion and metastasis. Its role in modulating cell signaling pathways makes it an interesting target for therapeutic interventions in both neurological disorders and cancer. Current studies are focusing on its functional implications in synaptic plasticity and tumor progression, providing valuable insights into IGSF11's diverse biological roles.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Brain and testis-specific immunoglobulin superfamily protein; Bt-IGSF; IgSF11; Immunoglobulin superfamily member 11; V-set and immunoglobulin domain-containing protein 3
Gene Aliases: BTIGSF; CXADRL1; IGSF11; VSIG3
Entrez Gene ID: (Human) 152404
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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