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Invitrogen
C19orf10 Polyclonal Antibody
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Product Details
PA5-61304
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human C19orf10. Recombinant protein control fragment (Product #RP-98885).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: YLYFTQFKAE VRGAEIEYAM AYSKAAFERE SDVPLKTEEF EVTKTAVAHR PGAFKAELSK LVIVAKASRT EL
Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 89%.
Target Information
The interleukins are a broad family of well characterized cytokines, primarily of hematopoietic cell origin. Cytokines are small, soluble proteins with pleiotropic effects on a variety of cell types. Cytokines have a regulatory function over the immune system and mediate aspects of inflammatory response. IL-25 (also called SF20/IL-25) is a secreted bone marrow stroma-derived growth factor cytokine that is derived from Th2 T-cells. IL-25 belongs to the IL-17 cytokine family and is capable of amplifying allergic type inflammatory responses by its actions on other cell types. IL-25 binds to mouse thymic shared antigen-1 and supports lymphoid cell proliferation. Infusion of mice with IL-25 induces IL-4, IL-5, and IL-13 gene expression. IL-25 induced mice also develop epithelial cell hyperplasia, increased mucus secretion, and airway hyperreactivity, suggesting that IL-25 may be an important mediator of allergic disease via production of IL-4, IL-5, IL-13 and eotaxin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CS010; IL 25; IL 27; interleukin 25; interleukin 27 working designation; interleukin-25; Interleukin25; MYDGF; Myeloid-derived growth factor; R33729 1; R337291; stromal cell-derived growth factor SF20; UPF0556 protein C19orf10
Gene Aliases: C19orf10; EUROIMAGE1875335; IL25; IL27; IL27w; MYDGF; R33729_1; SF20
UniProt ID: (Human) Q969H8
Entrez Gene ID: (Human) 56005
angiogenesis
positive regulation of protein phosphorylation
positive regulation of endothelial cell proliferation
apoptotic process
positive regulation of phosphatidylinositol 3-kinase signaling
IRE1-mediated unfolded protein response
negative regulation of apoptotic process
positive regulation of MAPK cascade
positive regulation of angiogenesis
positive regulation of transcription from RNA polymerase II promoter
positive regulation of protein kinase B signaling
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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