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Invitrogen
PLEKHJ1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-61857
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human PLEKHJ1. Recombinant protein control fragment (Product #RP-98922).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.4 mg/mL
Amount
40 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: FIEDPERKYH FECSSEEQCQ EWMEALRRAS YEFMRRSLIF YRNEIRKVTG KDPLEQFGIS EEARFQLSGL
Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 87%.
Target Information
The PLEKHJ1 (Pleckstrin Homology Domain Containing, Family J Member 1) gene encodes a protein that is involved in signal transduction and cytoskeletal organization. Located on chromosome 11, the PLEKHJ1 protein contains a pleckstrin homology (PH) domain, which facilitates its binding to phosphoinositides and the subsequent interaction with cellular membranes. This interaction is vital for various cellular processes, including the regulation of cell shape, motility, and intracellular trafficking. The precise biological functions of PLEKHJ1 are still being elucidated, but its role in these signaling pathways underscores its importance in maintaining cellular architecture and function. Alterations in PLEKHJ1 expression or mutations can have significant implications for cellular dynamics and have been linked to certain pathological conditions, including cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: guanine nucleotide releasing protein x; PH domain-containing family J member 1; PLEKHJ1; unnamed protein product
Gene Aliases: GNRPX
UniProt ID: (Human) Q9NW61
Entrez Gene ID: (Human) 55111
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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