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Invitrogen
Naked2 Polyclonal Antibody
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Product Details
PA5-61979
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human Naked2. Recombinant protein control fragment (Product #RP-96881).
Conjugate
Form
Liquid
Concentration
1.0 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: GHKRYRQKGR EGHSPLKAPH AQPATVEHEV VRDLPPTPAG EGYAVPVIQR HE
Highest antigen sequence identity to the following orthologs: Mouse - 75%, Rat - 77%.
Target Information
Cell autonomous antagonist of the canonical Wnt signaling pathway. May activate a second Wnt signaling pathway that controls planar cell polarity. Required for processing of TGFA and for targeting of TGFA to the basolateral membrane of polarized epithelial cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Dvl-binding protein NKD2; hNkd2; naked cuticle homolog 2; naked cuticle-2; Naked-2; NKD2, WNT signaling pathway inhibitor; Protein naked cuticle homolog 2
Gene Aliases: Naked2; NKD2
UniProt ID: (Human) Q969F2
Entrez Gene ID: (Human) 85409
exocytosis
positive regulation of protein processing
Wnt signaling pathway
negative regulation of Wnt signaling pathway
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
Golgi vesicle fusion to target membrane
protein localization to plasma membrane
negative regulation of canonical Wnt signaling pathway
positive regulation of protein localization to plasma membrane
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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