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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: TDLPKKPSKL ELSDLSKKFP QLGATPFPRK PLQPEVGEAP LKASLPEPGA PARKPLQPDE LSHPARPPSE PKSGAFPRKL WQP
Highest antigen sequence identity to the following orthologs: Mouse - 41%, Rat - 38%.
The protein encoded by this gene is similar to FYN binding protein (FYB/SLAP-130), an adaptor protein involved in T cell receptor mediated signaling. This gene is expressed and regulated during normal myelopoiesis. The expression of this gene is induced by retinoic acid and is inhibited by the expression of PML-RARalpha, a fusion protein of promyelocytic leukemia (PML) and the retinoic acid receptor-alpha (RARalpha).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: MGC39864; PML-RARA target gene encoding an Adaptor Molecule-1; PRAM; PRAM-1 protein
Gene Aliases: PML-RAR; PRAM-1
UniProt ID: (Human) Q96QH2
Entrez Gene ID: (Human) 84106
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