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Invitrogen
BDKRB2 Polyclonal Antibody
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Product Details
PA5-62254
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human B2R. Recombinant protein control fragment (Product #RP-89138).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: FSPWKISMFL SVREDSVPTT ASFSADMLNV TLQGPTLNGT FAQSKCPQVE WLGWLNTIQP
Highest antigen sequence identity to the following orthologs: Mouse - 50%, Rat - 47%.
Target Information
Bradykinin B2 receptor (BDKRB2) expression has been reported in blood, brain, eye, kidney, liver, lung, prostate, skin, small intestine, synovium, uterus, and vessel. ESTs have been isolated from colon, connective tissue, heart, heart/melanocyte/uterus, and kidney libraries. It is associated with G-proteins that activate a phosphatidylinositol-calcium second messenger system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: B-2 bradykinin receptor gene; B2 bradykinin receptor; B2-bradykinin receptor gene; B2R; BK-2 receptor; BK-2R; BK-2Rs; DKFZp686O088; G-protein coupled receptor; unnamed protein product
Gene Aliases: B2R; BDKRB2; BK-2; BK2; BKR2; BRB2
UniProt ID: (Human) P30411
Entrez Gene ID: (Human) 624
system process
smooth muscle contraction
inflammatory response
signal transduction
cell surface receptor signaling pathway
transmembrane receptor protein tyrosine kinase signaling pathway
G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
blood circulation
response to salt stress
regulation of vasoconstriction
vasoconstriction
vasodilation
regulation of vascular permeability
arachidonic acid secretion
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator
intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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