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Invitrogen
TMEFF1 Polyclonal Antibody
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Product Details
PA5-62420
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human TMEFF1. Recombinant protein control fragment (Product #RP-101483).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: DCPGGKGKSI NCSELNVRES
Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 90%.
Target Information
The TMEFF1 gene encodes the protein transmembrane protein with ependymin domain 1, which is involved in cellular signaling and neural development. TMEFF1, characterized by its transmembrane and ependymin-related domains, plays a role in the modulation of cell-cell interactions and signaling pathways essential for brain development and function. This protein is expressed predominantly in the central nervous system, where it influences neuronal differentiation and synaptic formation, contributing to the establishment and maintenance of neural circuits. TMEFF1 has been implicated in neuroprotective functions, where it supports neuronal survival in response to stress or injury. Additionally, its expression has been studied in the context of cancer biology, particularly in brain tumors, where TMEFF1 might impact tumor growth and progression through its effects on cell signaling and adhesion. Research continues to explore the specific mechanisms and interactions of TMEFF1 to better understand its roles in neural health and disease, particularly in neurodevelopmental disorders and cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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