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Invitrogen
PTPRD Polyclonal Antibody
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Product Details
PA5-63030
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human PTPRD. Recombinant protein control fragment (Product #RP-103750).
Conjugate
Form
Liquid
Concentration
0.10 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: GREVELKPYI AAHFDVLPTE FTLGDDKHYG GFTNKQLQSG QEYVFFVLAV MEHAESKMYA TSPYSDPVVS MDLDPQPITD EEE
Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.
Target Information
PTPRD is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of three Ig-like and eight fibronectin type III-like domains. Studies of the similar genes in chicken and fly suggest the role of this PTP is in promoting neurite growth, and regulating neurons axon guidance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: protein tyrosine phosphatase, receptor type, delta polypeptide; Protein-tyrosine phosphatase delta; rceptor-type tyrosine-protein phosphatase delta; Receptor-type tyrosine-protein phosphatase delta; unnamed protein product
Gene Aliases: 1110002J03Rik; 3000002J10Rik; B230219D21Rik; HPTP; HPTPD; HPTPDELTA; PTPD; PTPRD; R-PTP-delta; RPTPDELTA
UniProt ID: (Human) P23468, (Mouse) Q64487
Entrez Gene ID: (Human) 5789, (Mouse) 19266
phosphate-containing compound metabolic process
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
signal transduction
transmembrane receptor protein tyrosine phosphatase signaling pathway
nervous system development
neuron differentiation
negative regulation of JAK-STAT cascade
positive regulation of dendrite morphogenesis
regulation of immune response
modulation of synaptic transmission
positive regulation of synapse assembly
positive regulation of dendritic spine morphogenesis
presynaptic membrane assembly
presynapse assembly
regulation of postsynaptic density assembly
trans-synaptic signaling
trans-synaptic signaling by trans-synaptic complex
synaptic membrane adhesion
protein dephosphorylation
dephosphorylation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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