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Invitrogen
KIRREL3 Polyclonal Antibody
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Product Details
PA5-63287
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human KIRREL3. Recombinant protein control fragment (Product #RP-103252).
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: PTGMSFTNIY STLSGQGRLY DYGQRFVLGM GSSSIELCER EFQRGSLSDS SSFLDTQCDS SVSSSGKQDG YVQFDKASKA SASSSHHSQS SSQNSDPSR
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.
Target Information
The protein encoded by this gene is a member of the nephrin-like protein family. These proteins are expressed in fetal and adult brain, and also in podocytes of kidney glomeruli. The cytoplasmic domains of these proteins interact with the C-terminus of podocin, also expressed in the podocytes, cells involved in ensuring size- and charge-selective ultrafiltration. The protein encoded by this gene is a synaptic cell adhesion molecule with multiple extracellular immunoglobulin-like domains and a cytoplasmic PDZ domain-binding motif. Mutations in this gene are associated with several neurological and cognitive disorders. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Kin of IRRE-like protein 3; Kin of irregular chiasm-like protein 3; nephrin-like 2; Nephrin-like protein 2
Gene Aliases: KIAA1867; KIRRE; KIRREL3; MRD4; NEPH2; PRO4502; UNQ5923/PRO4502/PRO19814
UniProt ID: (Human) Q8IZU9
Entrez Gene ID: (Human) 84623
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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