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Invitrogen
B4GALT6 Polyclonal Antibody
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Product Details
PA5-63547
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human B4GALT6. Recombinant protein control fragment (Product #RP-103322).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: TTYLPENFTY SPYLPCPEKL PYMRGFLNVN VSEVSFDEIH QLFSKDLDIE PGGHWRPKDC KPRWK
Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 88%.
Target Information
This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene is a lactosylceramide synthase important for glycolipid biosynthesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Beta-1,4-galactosyltransferase 6; Beta-1,4-GalTase 6; beta4GalT-VI; Glucosylceramide beta-1,4-galactosyltransferase; LacCer synthase; Lactosylceramide synthase; UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 6; UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6; UDP-Gal:glucosylceramide beta-1,4-galactosyltransferase; UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 6; unnamed protein product
Gene Aliases: B4Gal-T6; B4GALT6; beta4Gal-T6
UniProt ID: (Human) Q9UBX8
Entrez Gene ID: (Human) 9331
lactosylceramide biosynthetic process
carbohydrate metabolic process
protein glycosylation
lipid metabolic process
sphingolipid metabolic process
glycosphingolipid biosynthetic process
ganglioside biosynthetic process via lactosylceramide
central nervous system neuron axonogenesis
central nervous system myelination
neuron maturation
glycosylation
carbohydrate derivative biosynthetic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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