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Invitrogen
ZFHX3 Polyclonal Antibody
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Product Details
PA5-63707
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human ZFHX3. Recombinant protein control fragment (Product #RP-101926).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: KAQVQVPQQS HQQILPQQQQ NQLSIAQSHS ALLQPSQHPE KKNKLVIKEK EKESQRERDS AEGGEGNTGP KETLPDA
Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 76%.
Target Information
Transcriptional repressor. It inhibits the enhancer element of the AFP gene by binding to its AT-rich core sequence. Regulator of myoblasts differentiation through the binding to the AT-rich sequence of MYF6 promoter and promoter repression. Down-regulates the MUC5AC promoter in gastric cancer. Miura Y., J. Biol. Chem. 270:26840-26848(1995). Morinaga T., Mol. Cell. Biol. 11:6041-6049(1991). Martin J., Nature 432:988-994(2004).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alpha-fetoprotein enhancer binding protein; Alpha-fetoprotein enhancer-binding protein; AT motif-binding factor 1; AT-binding transcription factor 1; unnamed protein product; ZFH-3; Zinc finger homeobox protein 3; Zinc finger homeodomain protein 3
Gene Aliases: ATBF1; ATBT; ATFB8; C16orf47; SCA4; ZFH-3; ZFHX3; ZNF927
UniProt ID: (Human) Q15911
Entrez Gene ID: (Human) 463
transcription regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
nucleic acid binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
zinc ion binding
enzyme binding
metal ion binding
negative regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
muscle organ development
circadian regulation of gene expression
negative regulation of myoblast differentiation
positive regulation of myoblast differentiation
regulation of neuron differentiation
positive regulation of cell adhesion
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
response to transforming growth factor beta
regulation of locomotor rhythm
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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