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Invitrogen
PRR14 Polyclonal Antibody
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Product Details
PA5-63828
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein fragment of Human PRR14 (Product #RP-98686).
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: IHRTSSTLRR RSRTTPGPEE GPSQKVDRAP QPTLVVMLED IASPRPPAEG FIDETPNFII PAQRAEPMRI VRQPTPPPGD LEPPFQPSAL PADPLESPPT APDP
Highest antigen sequence identity to the following orthologs: Mouse - 49%, Rat - 49%.
Target Information
The protein encoded by this gene tethers heterochromatin to the nuclear laminar scaffold by binding heterochromatin protein 1 (HP1) and the nuclear lamina. The tether is broken during mitosis and reforms quickly after mitosis, with the encoded protein first binding HP1 and then attaching to the nuclear lamina. This protein also has been shown to promote MyoD activity and skeletal myogenesis. Two transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Proline-rich protein 14
Gene Aliases: PRR14
UniProt ID: (Human) Q9BWN1
Entrez Gene ID: (Human) 78994
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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