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Invitrogen
SPAG4 Polyclonal Antibody
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Product Details
PA5-63985
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human SPAG4. Recombinant protein control fragment (Product #RP-103423).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Amount
5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: LSDITLQHPP PSVEHTGGAN SAPRDFAVFG LQVYDETEVS LGKFTFDVEK SEIQTFHLQN DPPAAFPKVK IQILSNWGH
Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 86%.
Target Information
The mammalian sperm flagellum contains two cytoskeletal structures associated with the axoneme: the outer dense fibers surrounding the axoneme in the midpiece and principal piece and the fibrous sheath surrounding the outer dense fibers in the principal piece of the tail. Defects in these structures are associated with abnormal tail morphology, reduced sperm motility, and infertility. In the rat, the protein encoded by this gene associates with an outer dense fiber protein via a leucine zipper motif and localizes to the microtubules of the manchette and axoneme during sperm tail development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: acrosomal protein ACR55; associated with outer dense fiber formation in elongating spermatids; cancer/testis antigen 127; Outer dense fiber-associated protein SPAG4; Sad1 and UNC84 domain containing 4; sperm tail protein; Sperm-associated antigen 4 protein; SUN domain-containing protein 4
Gene Aliases: CT127; SPAG4; SUN4
UniProt ID: (Human) Q9NPE6
Entrez Gene ID: (Human) 6676
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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